Aberrant cholesterol metabolism is increasingly appreciated to be essential for prostate cancer (PCa) initiation and progression. Transcript expression of the high-density lipoprotein-cholesterol receptor scavenger receptor B1 (SR-B1) is elevated in primary PCa. Hypothesizing that SR-B1 expression may help facilitate malignant transformation, we document increased SR-B1 protein and transcript expression in PCa relative to normal prostate epithelium that persists in lethal…
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Investigators at the University of British Columbia (UBC) Centre for Molecular Medicine & Therapeutics (CMMT) and BC Children’s Hospital have examined more than 25 years of data to reveal new insights into predicting the age of onset for Huntington disease. “This discovery may enable us to provide families with additional information,” said lead author Galen Wright, a research associate in…
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A prestigious Banting Postdoctoral Fellowship has been awarded to Dr. Jonathon Briggs, who is currently working in the Brumer lab at the University of British Columbia’s Michael Smith Laboratories. Briggs’ research involves learning more about how complex carbohydrates are broken down, transported and used by bacteria in the human gut. Study of these mechanisms gives a better understanding of how to best feed gut…
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Twenty-four doctoral students at UBC have received a Vanier Canada Graduate Fellowship, and three postdoctoral fellows have received a Banting Postdoctoral Fellowship. The announcement was made on May 16 by the Honourable Kirsty Duncan, Minister of Science, at Queen’s University, in Kingston, Ontario. Across Canada, 167 new Vanier Canada Graduate Scholarship recipients and 70 new Banting Postdoctoral Fellowship recipients were selected.…
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University of British Columbia researchers have developed a specialized microscope that has the potential ability to both diagnose diseases that include skin cancer and perform incredibly precise surgery—all without cutting skin. The researchers describe the technology in a study published today in Science Advances. “Our technology allows us to scan tissue quickly, and when we see a suspicious or abnormal cell…
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New MRI Study Assesses Myelin and Iron as Biomarkers in the Brain

A new computational tissue model from Dr. Alex Rauscher and his team has enabled the researchers to quantify brain myelin and iron from MRI scans, offering new clues as to the role of myelin and iron in tissue damage and disease progression in multiple sclerosis (MS). Published recently in the journal NMR Biomedicine, their paper reveals a difference in brain iron between people with MS, their…
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BC’s new school of biomedical engineering (BME) is closing in on a milestone of student gender parity. BME’s female enrolment rate is now 45.9 per cent which makes the BME program close to the faculty of applied science’s goal of achieving 50:50 parity in men and women enrolment. “Applied Science has worked aggressively to increase the enrolment of women across…
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YWCA Metro Vancouver is pleased to announce the recipients of its 36th annual Women of Distinction Awards. More than 1,300 guests and volunteers gathered on May 13, 2019 at the JW Marriott Parq Vancouver to honour inspiring nominees and their achievements. This year’s recipients are: ARTS, CULTURE & DESIGN Dana Claxton Dana is Department Head of the Department of Art History, Visual…
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Published in Clinical Cancer Research, the study found a small group of patients whose pancreatic cancer carried a rare trait that was potentially treatable with a targeted therapy often used to treat lung cancer. After receiving treatment, those patients’ health improved. Pancreatic cancer is currently the fourth-leading cause of cancer-related deaths in Canada, with 700 people diagnosed each year in British…
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Bacteria identify and respond to DNA damage using the SOS response. LexA, a central repressor in the response, has been implicated in the regulation of lysogeny in various temperate bacteriophages. During infection of Bacillus thuringiensis with GIL01 bacteriophage, LexA represses the SOS response and the phage lytic cycle by binding DNA, an interaction further stabilized upon binding of a viral protein, gp7.…
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