AbCellera, a leader in therapeutic antibody discovery from natural immune systems, today announced it has entered into an agreement with Gilead Sciences to support the discovery of therapeutic antibody candidates for infectious diseases. AbCellera will apply its expertise in single-cell screening of natural immune sources to generate rich panels of antibody candidates for evaluation by Gilead. Under the agreement, AbCellera…
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BioTalent Canada announced today that Mina Huang, Co-op Research & Development student with the Intestinal Team at STEMCELL Technologies, is the winner of BioTalent Canada’s 2019 Catalyst Award for Top New Hire. The announcement was made publicly at STEMCELL Technologies’ Station Street office in front of a group of peers and industry leaders. The winner will be awarded a cash…
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The Withers lab has been interested in using the technique of metagenomics to discover new enzymes for the removal of cell surface sugar antigens, such as those that define the A, B and O blood types. If the procedure described in this publication proves to be completely safe, it has the potential to broaden the supply of blood, since any A blood can be converted into universal donor O type. This could greatly assist inventory control in blood banks and help avoid the shortages that seem to happen all too often.
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Going toe-to-toe with cancer, especially pancreatic cancer, is never easy. Pancreatic cancer is inherently difficult to treat. But a new treatment, now in clinical trials at BC Cancer, has the potential to be a heavy hitter when combined with existing therapies. Developed by distinguished BC Cancer scientist Dr. Shoukat Dedhar, this treatment method doesn’t work on the tumours themselves, but rather…
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Dr. Jeannie Shoveller has been appointed as the new chairperson of the Canadian Institutes of Health Research (CIHR) Governing Council. This marks the first time a woman has served as chairperson of the council. “Women’s voices need to be heard around the decision-making table – yes, because it is 2019 – but also because women bring a unique perspective,” said the…
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On any given day, hospitals across the United States burn through some 16,500 liters (35,000 pints) of donated blood for emergency surgeries, scheduled operations, and routine transfusions. But recipients can’t take just any blood: For a transfusion to be successful, the patient and donor blood types must be compatible. Now, researchers analyzing bacteria in the human gut have discovered that microbes…
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Most treatments for multiple sclerosis (MS) target the adaptive immune and may ameliorate the patients’ clinical symptoms, but they have little or no effect on disease onset and progression. The 12 genes harboring pathogenic mutations for MS identified in this study have biological functions in linked innate immune pathways, and suggest that the dysregulation of innate immunity, not adaptive, is the initial step towards the development of disease.
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This study focuses on the area surrounding a pathogenic polyglutamine repeat in patients with Huntington disease (HD), which is predominantly encoded in the DNA by CAG codons. In a subset of HD patients that presented significantly earlier than expected based on their polyglutamine length, the authors identified a genetic variant where this codon had undergone a single substitution from CAA to CAG, increasing the length of the uninterrupted CAG repeat.
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An international team of researchers led by the University of British Columbia has made a scientific advance they hope will lead to the development of preventative treatments for multiple sclerosis (MS). In a study published today in PLOS Genetics, researchers found mutations in 12 genes believed to be largely responsible for the onset of MS in families with multiple members diagnosed with…
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