Timothy Caulfield’s article, “Microbiome research needs a gut check” published in the Globe and Mail, reminds us of just where we’re at in researching the microbiome – the vast array of bacteria, fungi, protozoa and viruses that live on and inside the human body. “Gut hype is everywhere” says Caulfield, who is one of many voices cautioning about over simplistic…
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Surprisingly, despite our extensive knowledge of the chemical compounds found in nature, there has never been a comprehensive, open-source database for researchers to store information on the chemistry produced by bacteria and fungi. Until now. Simon Fraser University associate professor Roger Linington and a team of international collaborators have created the Natural Products Atlas, which holds information on nearly 25,000 natural…
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The authors have found that ELF3, a transcription factor, is a new amplified oncogene in approximately 80% of all lung adenocarcinomas (LUAD), the largest subtype of lung cancer. Using a mouse model, they have found that LUAD cells that express ELF3 are selected for in implanted tumours, and ELF3 expression is required for tumour growth. They also saw that in human LUAD tumours, high expression of ELF3 is associated with poor patient outcome, indicating the importance of ELF3 to LUAD biology.
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Decipher Biosciences (formerly GenomeDx), a leader in the field of urologic cancer genomics, has announced a research collaboration with Dendreon Pharmaceuticals, a commercial-stage biopharmaceutical company and pioneer in the development of immunotherapy, to apply genomic tumor profiling using the Decipher® assay and GRID® software to identify prostate cancer patients on active surveillance who may benefit most from treatment with sipuleucel-T. PROVENGE®…
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Dr. Leonard Foster‘s students describes him as an outstanding scientist and mentor who cares deeply about his students’ learning, creativity, growing independence, career development, and wellbeing. He engages each individual on their own terms, drawing up their interests and ambitions, and actively seeks out ways or opportunities to help them fulfill these goals. Dr. Foster is consistently described as a…
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The Women’s Health Research Institute (WHRI) is very pleased to congratulate the recipients of the 2019 Women’s Health Research Institute Catalyst Grants. This competition was funded thanks to the dedicated support of the BC Women’s Health Foundation. This grant competition provides support for pilot studies in women’s and newborn’s health, which aim to generate preliminary data; test new approaches, methodologies…
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Robert Hogg has been appointed as the new Associate Dean, Research in the Faculty of Health Sciences (FHS). Hogg will lead the ongoing implementation of FHS’s strategic research plan and oversee various research projects and initiatives in each of the faculty’s six major research challenge areas. “I am excited to have Bob join the FHS leadership team,” says FHS dean Tania…
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The University of British Columbia and the University of Oxford have formalized a transatlantic partnership that will create a global network for training in clinical pharmacology. (L to R): Dr. Sultan Karim, Professor John Climax, and Dr. Dermot Kelleher UBC and Oxford have signed a memorandum of understanding to create a pathway for the exchange of people and ideas to…
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The authors used an automated tracking system to quantify 26 measures spanning morphology, locomotion, tactile sensitivity and habituation learning in 135 strains of C. elegans, each carrying a mutation in a gene associated with autism spectrum disorder. They found that loss of function mutations in many of these genes delayed development, and that many of the genes impaired the animal’s ability to habituate. The result was that many of the strains kept responding to sensory stimuli when they should have learned to stop.
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Joining Forces For Responsive And Responsible Research Funding

As BC’s health research funding agency, we think deeply about how to grow, improve and best support BC health research. Since our first Forward Thinking post, we’ve shared a series of blogs on health research funding and ‘helping-it-happen’. In this post, MSFHR’s President & CEO Dr. Bev Holmes discusses a new collaboration with like-minded funders to further research-on-research and maximize our investments. Forward Thinking is MSFHR’s blog focusing…
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