A promising new type of cell-based cancer treatment called CAR T-cell therapy exploits the power of the immune system to fight cancer. To grow in a laboratory, T cells require a rich source of nutrients and a warm environment—conditions that are unfortunately ideal for the growth of bacteria. Prior methods for screening cell-based therapy products rely on replication of contaminating bacteria so that they can be seen under a microscope—a process that can take up to a month. A new method developed by the Holt lab can be done in a day.
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Bold Therapeutics Inc., a clinical-stage biopharmaceutical company developing novel anti-cancer therapies, announced that it has received clearance from Health Canada to initiate a Phase 1b trial of its first-in-class anti-resistance therapeutic, BOLD-100, in combination with FOLFOX for the treatment of gastric, pancreatic, colorectal and bile duct cancers. “Based on compelling preclinical efficacy in combination with a wide range of anti-cancer agents, we…
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Sometime in the next day or two, a medical courier will deliver a styrofoam cooler to the offices of AbCellera, a biotech firm headquartered in downtown Vancouver, British Columbia. Inside the box, packed in dry ice, will be a vial of blood prepared by researchers at the US National Institutes of Health, who drew it from a patient infected with the…
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While every research project is built with the goal of one day making the transition from basic research to applied science, most scientific discoveries will not make an immediate impact beyond the lab. Though this may seem like a counterproductive or at the very least inefficient system, those discoveries that do make the leap into the real world are invariably…
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Congratulations CIHR Project Grant Recipients!

Congratulations to the BC Children’s and BC Women’s investigators who were awarded funding through the highly competitive Canadian Institutes of Health Research (CIHR) Project Grant Fall 2019 competition. Our research community received more than $8 million in new research and bridge grants. Many of the investigators who were successful in this competition benefited from the expertise of Dr. Dawn McArthur,…
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Once Listeria bacteria have entered a cell, these microbes hijack the host cell’s actin filament polymerization machinery to generate a rocket-like structure at one end of the bacteria. These rocket-like structures enable the bacteria to move within the cell, and that enable the cell-to-cell transfer of the microbes. Although the bacterial protrusions press into the neighbouring cells, this is not enough to allow for the bacteria to enter those neighbouring cells.
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Twelve outstanding BC Cancer researchers have received significant grants totalling over $4.6 million from the federal government. The funding provided by the Canadian Institutes of Health Research (CIHR) will allow them and their teams to pursue research breakthroughs in cancer, leading to a better understanding of cancer and improved outcomes. The below are the recipients from the 2019 Fall Project…
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Patrick Keeling, a botanist who studies protists, single-celled organisms with a complex evolutionary history, has been awarded UBC’s top research accolade, the Jacob Biely Faculty Research Prize. Keeling‘s work has uncovered clues into the evolution of the parasites that cause diseases such as malaria, as well as provided a better understanding of coral biology. He has discovered a number of…
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UBC Women in Science 2020

International Day of Women and Girls in Science takes place every year on February 11. Spearheaded by the United Nations, this day promotes full and equal access to participation in science, technology, and innovation for women and girls. The Faculty of Science is supporting this day by featuring ten inspiring women researchers who are making their mark at UBC and…
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