Frontotemporal lobar degeneration (FTLD) is a devastating and progressive disorder, and a common cause of early onset dementia. Progranulin (PGRN) haploinsufficiency due to autosomal dominant mutations in the progranulin gene (GRN) is an important cause of FTLD (FTLD-GRN), and nearly a quarter of these genetic cases are due to a nonsense mutation. Premature termination codons (PTC) can be therapeutically targeted…
Read More
Derm-Biome Pharmaceuticals, Inc, a private Vancouver based start-up biopharmaceutical company focused on skin health and healthy ageing, is pleased to announce that one of its topical drugs produced significant, and dose dependent inhibitory effects in a well established mouse model of atopic dermatitis (AD). AD (eczema) is a chronic inflammatory skin disease often linked to depression and a decreased quality…
Read More
Genome BC is ]launching a rapid response funding program to invest in promising research and innovation projects with the real potential to address urgent challenges related to the COVID-19 pandemic. The initiative is using a specifically designed process for reviewing applications and providing funds for approved projects within days. This rapid response will enable researchers and innovators to launch projects…
Read More
On March 21, 2020, the virology laboratory at St. Paul’s Hospital started using a new high throughput, fully automated COVID-19 testing method – a first in Canada. “Testing is the key to COVID-19 diagnostics (for patient care) and surveillance (for public health),” says Dr. Marc Romney. “And high-volume testing capacity is critical in our fight to contain and control the spread…
Read More
Canada’s largest biotechnology company, Vancouver’s STEMCELL Technologies, has been making significant contributions to the fight against COVID-19. Human tissue culture systems developed by STEMCELL were used by researchers at China’s Centre for Disease Control (CDC) to grow lung airway cells that could successfully propagate the novel coronavirus SARS-CoV-2. Scientists were then able to isolate the virus, obtain the viral gene sequence, and quickly make…
Read More
The authors describe a very interesting mechanism for the regulation of symmetric versus asymmetric cellular division. The work describes a process whereby mitotic spindle orientation dictates the inheritance of an integrin, α6b1, which is a marker of epithelial stem cells, and provides the growth/division signal. They also identify, for the first time, that Stat3 can regulate mitotic spindle orientation through a non-transcriptional pathway.
Read More
Five research teams at the University of British Columbia are collectively receiving $2.3 million in federal funding for research to help tackle the COVID-19 outbreak. The teams, led by UBC researchers Horacio Bach, Artem Cherkasov, Eric Jan, Jeffrey Joy and Dr. James Russell, are working on developing and implementing measures to rapidly detect, neutralize, manage, and reduce the transmission of…
Read More

SFU Student’s Honours Project Leads to BC-CfE Job

As a curious, keen problem solver who works to better understand HIV molecular virology, Hanwei Sudderuddin’s experiences with the Faculty of Health Sciences (FHS) have prepared him for his current work with the BC Centre for Excellence in HIV/AIDS (BC-CfE). After becoming intrigued with FHS professor Zabrina Brumme’s research upon listening to her speak as a guest for his FHS immunology class,…
Read More

Canada’s Plan to Mobilize Science to Fight COVID-19

The Government of Canada is supporting our country’s researchers as they do critical work to protect the health and safety of all Canadians, and people around the world, during the COVID-19 outbreak. The Prime Minister, Justin Trudeau, today announced support to quickly mobilize Canadian researchers and life sciences companies to support large-scale efforts towards countermeasures to combat COVID-19, including potential…
Read More
Canada’s strength in regenerative medicine (RM) and cell and gene therapies is a result of efforts that take place from sea to shining sea. Western Canada’s growing RM community significantly increases Canada’s competitiveness on the global playing field through its leading-edge research, advanced commercialization abilities, and excellent education and training programs. Prowess in research The region’s renowned researchers aim to…
Read More