The Canadian Institutes for Health Research has announced its latest CIHR Project Grants and 32 members of the UBC Faculty of Medicine were awarded more than $17.2 million in grants including a bridge grant.

A total of $20.3 million was awarded to UBC researchers for 31 projects at the university and its affiliated health authority research centres. The CIHR Project Grant is a part of the $275 million that was awarded nationally to support Canadian researchers to study the full spectrum of health issues affecting the lives of Canadians.

The UBC Faculty of Medicine recipients and their project titles are:

Juan Antonio Avina-Zubieta, Clinical Assistant Professor in the Division of Rheumatology and John Esdaile, Professor in the Division of Rheumatology
Risk of Retinal Toxicity in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis on Long-term Hydroxychloroquine Therapy, $707,625 over five years.

Nick Bansback and Eugenia Oviedo-Joekes, Associate Professors in the School of Population and Public Health
Network Meta-Analysis of Opioid Agonist Treatments for street opioid users, $145,350 over 1.5 years.

Alexander G. Beristain, Assistant Professor in the Department of Obstetrics and Gynaecology in the Division of Maternal Fetal Medicine
Cellular dynamics at the maternal-placental interface, $619,650 over five years.

Carolyn J. Brown, in the Department of Medical Genetics
Functional characterization of genomic DNA elements regulating epigenetic silencing, $971,550 over five years.

Liam Brunham, Assistant Professor in the Department of Medicine and Simon Pimstone, Clinical Associate Professor in the Department of Medicine
Improving the identification and treatment of young adults with heart disease: the Study to Avoid cardioVascular Events in British Columbia (SAVE BC), $654,075 over five years.

Elizabeth Conibear, Associate Professor of Medical Genetics in the Department of Biochemistry and Molecular Biology
Regulating the dynamic cycling of palmitate on proteins, $745,875 over five years.

Edward Conway, Professor in the Department of Medicine and Director of the Centre for Blood Research
Characterization of a novel cofactor for tissue factor (TF) that enhances its pro-thrombotic and pro-inflammatory activities, $826,200 over five years.

Hélène Côté, Associate Professor in the Department of Pathology and Laboratory Medicine
The BCC3 cohort: Cellular aging in women living with HIV, $822,375 over five years.

Angela Devlin, Associate Professor, Division of Endocrinology, Pediatrics
Maternal Folic Acid and Vitamin B12 intake During Pregnancy and Type 2 Diabetes Risk in Offspring, $485,775 over five years.

Cathie Garnis, Associate Professor in the Department of Surgery
Blood based biomarker for the early detection of recurrent head and neck cancer, $539,324 over four years.

Gillian Hanley, Assistant Professor in the Department of Obstetrics and Gynaecology
The effectiveness and cost-effectiveness of opportunistic salpingectomy for ovarian cancer prevention, $302,176 over four years.

LeAnn Howe, Associate Professor in the Department of Biochemistry and Molecular Biology
Regulation of chromatin structure on transcribed genes and newly replicated DNA, $535,500 over five years.

Michael Hunt, Associate Professor in the Department of Physical Therapy
Linking biomechanical and imaging outcomes to better understand the effects of running on knee joint health, $677,025 over five years.

Aly Karsan, Professor in the Department of Pathology and Laboratory Medicine
Hematopoietic stem cell aging, $914,175, over five years.

Janel Kopp, Assistant Professor in the Department of Cellular and Physiological Sciences
Role of inflammation during the genesis of intraductal papillary mucinous neoplasia associated pancreatic ductal adenocarcinoma, $1,090,125, over five years.

Kuo-Shyan Lin, Associate Professor in the Department of Radiology
Cleavable linkers to reduce kidney uptake of peptide radiopharmaceuticals, $772,650 over five years.

Amee Manges, Associate Professor in the School of Population and Public Health
Fecal microbiota transplantation (FMT) for intestinal decolonization of multidrug-resistant opportunistic pathogens, $566,100 over five years.

Ryan McNeil, and Jade Boyd, Assistant Professors in the Department of Medicine
Housing and overdose risk environments: A community-based participatory research study, $650,632 over four years.

Katherine Plewes, Clinical Assistant Professor in the Department of Medicine
Evaluating the renoprotective effect of acetaminophen in pediatric severe falciparum malaria: A randomized controlled trial, $971,551 over three years.

Arman Rahmim, Associate Professor of Radiology
Quantitative PSMA Targeted Imaging of Prostate Cancer Patients, $631,124 over four years.

Neil Reiner, Professor in the Department of Medicine
Novel Mechanisms of Leishmania Pathogenesis, $730,575 over five years.

Regina Renner, Clinical Associate Professor in the Department of Obstetrics and Gynaecology, Bonnie Henry, Clinical Associate Professor in the School of Population and Public Health
The Canadian Surgical and Medical Abortion Provider Survey (CAPS), $407,780 over four years.

John Staples, Clinical Assistant Professor in the Department of Medicine
Motor vehicle crash risk after cardioverter-defibrillator implantation: A population-based evaluation, $180,000 over three years.

Sheila Teves, Assistant Professor the Department of Biochemistry and Molecular Biology
Transcriptional memory and plasticity in embryonic stem cells, $852,975 over five years.

Yuzhuo Wang, Professor in the Department of Urologic Sciences
Function and therapeutic potential of SUV420H2 in neuroendocrine prostate cancer, $956,250 over five years.

Wei Zhang, Assistant Professor in the School of Population and Public Health
Improving Health Economic Evaluation: Better Measures of Work Productivity Losses due to Illness in Canada, $436,048 over 4.5 years.

Priority Announcement Bridge Grant

Rizhi Wang, Professor in the School of Biomedical Engineering
Bone hypermineralization in older men and women and its impact on hip fragility, $100,000.