Bold Therapeutics Inc., a clinical-stage biopharmaceutical company developing novel anti-cancer therapies, announced that it has received clearance from Health Canada to initiate a Phase 1b trial of its first-in-class anti-resistance therapeutic, BOLD-100, in combination with FOLFOX for the treatment of gastric, pancreatic, colorectal and bile duct cancers. “Based on compelling preclinical efficacy in combination with a wide range of anti-cancer agents, we…
Read More
Sometime in the next day or two, a medical courier will deliver a styrofoam cooler to the offices of AbCellera, a biotech firm headquartered in downtown Vancouver, British Columbia. Inside the box, packed in dry ice, will be a vial of blood prepared by researchers at the US National Institutes of Health, who drew it from a patient infected with the…
Read More
While every research project is built with the goal of one day making the transition from basic research to applied science, most scientific discoveries will not make an immediate impact beyond the lab. Though this may seem like a counterproductive or at the very least inefficient system, those discoveries that do make the leap into the real world are invariably…
Read More

UBC Women in Science 2020

International Day of Women and Girls in Science takes place every year on February 11. Spearheaded by the United Nations, this day promotes full and equal access to participation in science, technology, and innovation for women and girls. The Faculty of Science is supporting this day by featuring ten inspiring women researchers who are making their mark at UBC and…
Read More
It was nearly two years into one of her projects that Dr. Lin Luo (pictured) realized something wasn’t right. She had been using the Cre-loxP system—an approach frequently used to knock out gene expression in specific cell types in mice and other animals—to study functions of the Calsyntenin-3 protein. After months of troubleshooting, she realized the gene wasn’t just being…
Read More

How the Power of T-Cells May Lead to an HIV Cure

Dr. Mark Brockman, a BC Centre for Excellence in HIV/AIDS (BC-CfE) Scientific Associate, recently presented at St. Paul’s Hospital as part of the BC-CfE’s Forefront Lecture series on the potential of using host T cells to eliminate the HIV viral reservoir. One of the principal challenges in achieving long-term ART-free HIV remission or a cure is the existence of a…
Read More
The BC Diabetes Research Network is delighted to announce episode 2  of our official podcast: “Diabetes: From Beta Cells to Bicycles“. Episode 2 launched February 5, 2020. In our second episode, host Krista Lamb is joined by BC Diabetes Research Network trainee and UBC PhD student Priye Iworima, who works in Dr. Timothy Kieffer’s lab at UBC’s Life Sciences Institute. Her current research…
Read More
The invention of vaccines for disease prevention is often cited as one of the miracles of modern medicine. New research from Simon Fraser University suggests that tailoring vaccines based on geography and other factors could substantially reduce overall rates of bacterial disease. Professor Caroline Colijn, who holds a Canada 150 Research Chair in Mathematics for Evolution, Infection and Public Health,…
Read More
Blood banks have long known about high-quality donors — individuals whose red blood cells stay viable for longer in storage, and in the recipient’s body. Now, a new device developed at UBC is showing promise as a method to identify these “super” donors, potentially helping more than 4.5 million patients who need blood transfusions every year in Canada and the…
Read More