MS Researcher-Led Event Encourages Teenagers to Choose Science

In Grade 10, fifteen- and sixteen-year-olds begin making the academic decisions that may shape their lives, opting for electives in the sciences or the arts. What they choose will influence where they plan to go to university, what they plan to study, and who they ultimately become. For many scientists, their earliest interest in science is sparked by someone else.…
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 Pascal Biosciences Inc. (TSX.V:PAS) (“Pascal” or the “Company”) today announced the Company has discovered certain cannabinoids that enhance the immunogenicity of tumor cells, rendering them more susceptible to recognition by the immune system. This discovery is important because the leading class of new cancer fighting agents, termed “checkpoint inhibitors”, activates the immune system to destroy cancer cells. Enhancing recognition of cancer…
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A Vancouver team led by TFRI-funded investigator Dr. David Huntsman has discovered an important therapeutic target for treating small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). This is a rare, but extremely lethal, ovarian cancer in young women with no effective treatment. The present study, published in The Journal of Pathology (June 2017), suggests that SCCOHT tumour cells need the activity of…
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New MS Model Provides Hope for Better Understanding of Disease Pathology

Until now, researchers studying multiple sclerosis (MS) in mouse models have relied on models heavily weighted towards processes secondary to an autoimmune trigger. While discoveries made through these models have informed later translational research and clinical trials to improve drug treatment for people living with MS, a lack of a model for the unique biological process by which the disease…
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The British Columbia-led Digital Technology Supercluster is one of the funding recipients for the Government of Canada’s Innovation Supercluster Initiative, Minister Navdeep Bains announced today. In May 2017, Minister Bains announced a nationwide initiative to create up to five superclusters that will supercharge Canada’s regional innovation ecosystems and “build Canada as a global centre for innovation.” Superclusters are innovation hotbeds,…
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A particular gene mutation associated with an inherited form of Parkinson’s disease (PD) offers new clues that call into question a controversial theory that changes associated with PD may begin in a different area of the brain. Idiopathic PD, a spontaneous form of the disease, affects the dopamine system and is treated with replacement therapy to restore the brain’s chemical…
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An astonishing number of viruses are circulating around the Earth’s atmosphere – and falling from it – according to new research from scientists in Canada, Spain and the U.S. The study marks the first time scientists have quantified the viruses being swept up from the Earth’s surface into the free troposphere, that layer of atmosphere beyond Earth’s weather systems but…
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Zucara Therapeutics Receives Funding to Advance Lead Drug Candidate

Zucara Therapeutics Inc., a pre-clinical life sciences company advancing a novel long-term therapeutic approach to prevent hypoglycemia in patients with diabetes, has received support of up to $350,000 from the National Research Council of Canada Industrial Research Assistance Program (NRC IRAP). In addition, The Centre for Drug Research and Development (CDRD) and MaRS Innovation have contributed follow on funding to…
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Faculty of Medicine scientists have found that a drug currently being tested for autoimmune disorders of the blood might also hold promise for treating esophageal cancer. Concern is growing worldwide about esophageal cancer due to its abysmal survival rates, with only 14 per cent of Canadian patients alive five years after diagnosis. It’s one of the few cancers that is…
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Using Human Kidney Organoids to Model Disease

There is an urgent need for curative therapies to treat kidney failure. In 2015, over 21,000 patients in Canada received dialysis to treat kidney failure. Another 2,500 patients received a kidney transplant and 215 died on the waiting list. As part of an ongoing collaboration, the laboratories of Dr. Kelly M. McNagny (UBC, CBR PI) and Dr. Benjamin S. Freedman…
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