Vancouver virtual life sciences company Novelogics Biotechnology Inc. has partnered with the Centre for Drug Research and Development (CDRD) to work on an innovative cancer treatment. Novelogics, which focuses on using the immune system to eliminate tumours in ways that have fewer side effects than traditional methods, has developed a technology that involves the discovery and development of antibodies that…
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My laboratory is focused on the creation and application of computational software and methods for the analysis of human genome sequences. In particular we increasingly focus on the analysis of non-coding genetic alterations that alter gene expression, and apply our methods to the identification of disease-causing variations for oediatric rare disease (for patients at BC Children's Hospital and around the world).
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Faculty of Medicine scientists have uncovered seven new subtypes of ovarian cancer, which could result in new treatment strategies for some ovarian cancer patients including those that do not respond well to chemotherapy. The discovery, published in Nature Genetics, analyzed the genetic information of more than 100 ovarian cancer patients in order to identify abnormalities in the DNA of ovarian cancer…
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Congratulations to Drs. Collins, Daugaard & Wang on being awarded five-year grants in the CIHR Project Grant: Fall 2016 competition. Dr. Wang is also a co-investigator on a five-year grant awarded to Dr. He at University Health Network (Toronto). Congratulations also to Dr. William Morris of the BC Cancer Agency and his research team, including our Centre’s Dr. Alan So,…
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My research is and has been focused on the role of genome instability in stem cells in aging and cancer. My lab has a track-record of developing novel research tools, many of which are still in widespread use e.g. commercialized by StemCell and other biotech companies. These include monoclonal antibodies, an IL-6 dependent cell line, cell separation techniques and methods to measure the length of telomere repeat in chromosomes and cells. Recently, we developed a powerful single cell sequencing technique called Strand-seq. We now want to use...
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Cancer-causing gene mutations were found in the pelvic lesions of women with a typically non-cancerous gynecological disorder called endometriosis, a study by Vancouver scientists published Wednesday by the New England Journal of Medicine shows. Endometriosis causes intense pelvic pain, menstrual abnormalities and even infertility. It is characterized by tissue that normally lines the uterus migrating outside the organ, causing lesions throughout the pelvic cavity. The bumpy…
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(Left to right) Dr. Fabio Rossi, William Kennedy, Roza Vaez Ghaemi, Dr. Katharina Rhothe, Stephanie Campbell, Sanam Shafaatablab, and Dr. Allen Eaves at the BC Regenerative Medicine Symposium. On May 10th, scientists and trainees in the field of stem cell biology attended the first ever BC Regenerative Medicine Symposium at the UBC Pharmaceutical Sciences building. The full day event featured…
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Zymeworks Inc. today announced the closing of its initial public offering of 4,500,000 common shares at an initial offering price of U.S.$13.00 per share, for a total of U.S.$58,500,000 in aggregate gross proceeds. Zymeworks expects to use the net proceeds from the offering to further develop and advance its pipeline of product candidates and to increase its liquidity. In addition,…
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UBC Faculty of Medicine researchers have found that reducing twin and triplet pregnancies to singleton or twin pregnancies was associated with a substantial reduction in complications, such as pre-term birth and very pre-term birth. Although rates of death and serious illness were not lower among all multi-fetal pregnancies that were reduced, pregnancies that resulted from fertility treatments did show a…
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Scientists in Vancouver have developed a new screening tool that reveals the genetic signature of an individual’s hepatitis C virus so that doctors can customize their treatment. The tool, funded by Genome B.C. and devised by researchers at the B.C. Centre for Excellence in HIV/AIDS, could save money and lives, said Anita Howe, scientific lead for the hepatitis C program.…
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