Last week, UBC and the Advanced Molecular Biology Laboratory hosted its annual Girls-Only Maker Camp, a week-long camp focused on STEAM (science, technology engineering, art, and math) education and designed for girls entering grades seven and eight.  Hosted by Dave Ng, the schedule included basic programming workshops, craftivism and Ugly Doll creation (by Kim Werker, read about her post here), breadboarding and circuit building, metal…
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In this manuscript, the authors describe a completely synthetic, efficient, and highly reproducible means for generating human T-ALL de novo from normal cord blood progenitors. They show that these synthetic leukemias appear indistinguishable from tumors arising spontaneously in human patients and undergo clonal evolution in vivo with acquisition of secondary mutations that are seen recurrently in natural leukemias.
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For the first time, scientists have captured high-resolution, three-dimensional images of an enzyme in the process of precisely cutting DNA strands. The images—captured using a technique called cryogenic electron microscopy, or cryo-EM—reveal new information about how a gene-editing tool called CRISPR-Cas9 works, which may help researchers develop versions of it that operate more efficiently and precisely to alter targeted genes.…
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Males who suffer debilitating scrotal pain can now sign up for a new study using an old but reformulated numbing medication with lidocaine. Nearly five per cent of males can suffer so much that mere walking can be painful if they have chronic pain in their testicles and scrotum, the latter of which are the sacs of skin surrounding the…
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The towering, hundred-year-old Sitka spruce trees growing in the heart of Vancouver Island’s Carmanah Valley appear placid and unchanging. In reality, each one is packed to the rafters with evolutionary potential. UBC researchers scraped bark and collected needles from 20 of these trees last summer, sending the samples to a lab for DNA sequencing. Results, published recently in Evolution Letters, showed that a…
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Jonathan Choy – The role of IL-17 receptor A in transplant rejection Organ transplantation is the only treatment for end-stage organ failure. As such, it is a potentially curative procedure for devastating conditions such as kidney, heart and liver disease. The success of organ transplantation is limited by the rejection of grafts by the immune system of recipients. Activation of…
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ProtoKinetix, Incorporated (www.protokinetix.com) (the “Company” or “ProtoKinetix”) (OTCQB:PKTX) has reached the mid-point of 3rd stage of testing in retinal cell replacement therapy at the University of British Columbia. Functionality testing on experimental models three months post-transplant show encouraging results. We anticipate results from six-month post-transplant to be available within the next 4-5 weeks. The study includes two experimental models over…
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Understanding hereditary cancer is the difference between life and death for Chiquita Hessels. In 2011, just ten months after her mother’s death from breast cancer, and one month after her maternal aunt’s passing from bowel and jaw cancer, Chiquita herself was diagnosed with breast cancer. Chiquita sought advice about whether there was a hereditary connection behind her family’s cancer history.…
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Welcome to the BCREGMED career column where we feature scientific professionals in British Columbia. For this issue, we have Dr. Sharmin Esmailzadeh, Account Manager– Cell Culture Products, for STEMCELL Technologies. Describe a typical day in your position? What are your day-to-day activities like? Usually I start my day with responding to emails. I visit customers in Vancouver 2-3 days/week. Some…
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Two UBC Faculty of Medicine members have been named to BNN Bloomberg’s 2019 Top 40 Under 40 list which recognizes Canada’s next leaders. Dr. Caitlin Dunne, clinical assistant professor in the department of obstetrics and gynaecology Caitlin Dunne and Zachary Laksman are among 44 recipients chosen from more than 850 nominees by an independent advisory board of business leaders from across Canada.…
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