Right now, 25% of children who survive blood and marrow transplants go on to develop chronic graft-versus-host disease (cGvHD), an incurable condition that can cause lifelong pain and disability. “Blood and marrow transplants can cure cancer and immune disease in patients who have few other treatment options, but they also can cause cGvHD,” says Dr. Kirk Schultz. “We want to preserve…
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When we talk about female representation in science, we’re rarely talking about test subjects. We tend to want more women behind the microscope, not under it. Neuroscience is one of the most skewed fields when it comes to testing on female physiology. One review found single-sex brain studies using male animals outnumbered those using females 6.7 to one. Aarthi Gobinath, a…
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REVIEW: Functional Horizontal Gene Transfer from Bacteria to Eukaryotes

Bacteria influence eukaryotic biology as parasitic, commensal or beneficial symbionts. Aside from these organismal interactions, bacteria have also been important sources of new genetic sequences through horizontal gene transfer (HGT) for eukaryotes. In this Review, we focus on gene transfers from bacteria to eukaryotes, discuss how horizontally transferred genes become functional and explore what functions are endowed upon a broad…
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Qu Biologics Inc., a biopharmaceutical company developing Site Specific Immunomodulators (SSIs), a unique platform of immunotherapies designed to “reboot” the body’s innate immune system, has just published collaborative research with Dartmouth College detailing the mechanism of action and efficacy of Qu’s lung-targeted SSI, QBKPN, for the treatment of lung cancer. It has long been recognized that acute infection can potentially trigger the…
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Cited Podcast Wins Top Journalism Award

In two small offices of the Michael Smith Laboratories, among the controlled chaos of labs and data, a small team of industrious journalists record a radio show and podcast called Cited. Last month, their hard work was rewarded with one of British Columbia’s most prestigious awards for journalism: The Jack Webster Award in Feature and Enterprise Reporting, for their episode The Heroin Clinic. Cited originally…
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The VERO study is the first properly designed and powered clinical trial comparing antiresorptive with bone anabolic therapy with fracture as the primary endpoint. Although it makes intuitive sense to first build bone and then preserve improved bone strength, the cost as well as the lack of proven anti-fracture superiority has led to the underutilization of bone anabolic therapy…
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Tommy Douglas. Terry Fox. Michael Bliss. Judith Hall. These renowned individuals are among the 125 laureates of the Canadian Medical Hall of Fame(CMHF), which recognizes Canadian heroes whose work has advanced health. Established in 1994, the national charitable organization aims to inspire pursuit of careers in the health sciences, while celebrating the country’s rich medical history. In April of 2018, an induction ceremony will see Canadian…
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As part of its Industry Innovation Program (I² Fund), Genome BC is investing CAD $750,000 in a local microbiome testing company—Vancouver-based Microbiome Insights (MBI), which provides next-generation-sequencing-based analytical testing and consulting services to microbiome researchers in academia and industry. The new funding adds to the company’s recent round of equity financing, which closed in October. Microbiomes are the communities of…
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We are interested in developing enrichment or cultivation approaches needed to directly test the hypotheses proposed in the manuscript. We also want to integrate our findings into a recently developed pathway-centric numerical model describing coupled biogeochemical cycling in the Saanich Inlet water column. We use Saanich Inlet as a model ecosystem for studying microbial community…
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Qu Biologics Inc., a biopharmaceutical company developing Site Specific Immunomodulators (SSIs), a unique platform of immunotherapies designed to “reboot” the body’s innate immune system, has just published collaborative research with Dartmouth College detailing the mechanism of action and efficacy of Qu’s lung-targeted SSI, QBKPN, for the treatment of lung cancer. It has long been recognized that acute infection can potentially trigger the…
Read More