Genome BC is pleased to announce $1 million in funding to Aspect Biosystems (Aspect), a privately held biotechnology company focused on commercializing cutting-edge 3D bioprinting technologies. Aspect’s Lab-on-a-Printer™ 3D bioprinting platform technology enables the rapid creation of functional living tissues. The therapeutic applications are broad and profound and have attracted the attention of global pharmaceutical and biotechnology companies. “Genome BC’s…
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A dozen years ago beekeepers started reporting that frightening numbers of their honeybees (Apis mellifera) were mysteriously dying. Scientists have since discovered multiple reasons, but “diseases are by far the main cause of problems with honeybee health right now,” says Leonard Foster, professor of biochemistry and molecular biology at the University of British Columbia. The insects are afflicted by scourges…
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Oncolytic Viruses as Engineering Platforms for Combination Immunotherapy

To effectively build on the recent successes of immune checkpoint blockade, adoptive T cell therapy and cancer vaccines, it is critical to rationally design combination strategies that will increase and extend efficacy to a larger proportion of patients. For example, the combination of anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA4) and anti-programmed cell death protein 1 (PD1) immune checkpoint inhibitors essentially…
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When we speak of the economy, we tend to talk of it in terms of its health. A declining economy is lethargic and sluggish, while a growing one is vibrant and robust. An often overlooked, yet integral, contributor to the health of the Canadian economy is the pharmaceutical industry and the partnerships it creates – partnerships to develop new innovative…
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Viral Proteins as a Potential Driver of Histone Depletion in Dinoflagellates

The packaging of DNA with histones is a hallmark of eukaryotic chromosomes.  One surprising exception is dinoflagellates, a group of unicellular eukaryotic algae, which have abandoned histones as the primary DNA packaging protein and instead employ a viral-derived proteins termed dinoflagellate-viral-nucleoproteins (DVNPs).  In this study, we sought to understand the molecular events…
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Five UBC teams met success for their innovative ideas at the intersection of health sciences and natural sciences and engineering research, in the form of CIHR’s NSERC Partnered Collaborative Health Research Projects ─ Fall 2017 Competition. Four LSI PIs are part of three of these five teams, a testament to the strong tradition of cross-disciplinary collaborations at the LSI.
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“Educational neuroscience is really an emerging field – with just five centres around the world, we’re proud to be the sixth, and the first in Canada,” says Dr. Lara Boyd. “So far, it’s been fascinating to learn from our colleagues in the field.” Dr. Boyd and several other researchers at the Djavad Mowafaghian Centre for Brain Health are currently taking part…
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Researchers at UBC and in Toronto have shown that a three-minute version of a brain stimulation treatment for hard-to-treat depression is just as effective as the standard 37-minute version. Repetitive transcranial magnetic stimulation (rTMS) uses magnetic field pulses to non-invasively stimulate a part of the brain called the dorsolateral prefrontal cortex, which is associated with mood regulation. The researchers compared…
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After years of intensive research and development, cell therapies are finally having their moment. In the past year, the FDA has approved two CAR-T cell (chimeric antigen receptor T-cell) therapies, with stem cell treatments in hot pursuit as they enter late-stage clinical trials. While regulatory body recognition is an important milestone for the field, great challenges in the long-term sustainability…
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bioLytical Laboratories, a world leader in rapid infectious disease tests, has been named the LifeSciences BC Growth Stage MedTech Company of the Year. This was one of several awards presented to distinguished organizations and leaders in the life sciences ecosystem at the 2018 Annual LifeSciences BC Awards dinner held at the Fairmont Hotel Vancouver. bioLytical is the developer and manufacturer of INSTI®,…
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