Peter Wall Institute International Research Roundtables Awarded

The Institute is pleased to announce the recipients of the International Research Roundtable Awards. These research awards foster excellence in research and serve as a catalyst for collaborative research between international and UBC scholars. The roundtables provide scholars, community leaders, artists, policy makers and others with unique opportunities to explore broad themes within an interdisciplinary environment for two to five days.…
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Simon Fraser University’s VentureLabs® is receiving $3 million in funding from Western Economic Diversification Canada to establish a scale-up and soft-landing centre within its Vancouver-based business accelerator. The funding was announced today by the Hon. Navdeep Bains, Minister of Innovation, Science and Economic Development. The funds are part of a $3.7 million announcement aimed at supporting initiatives that will help western Canadian entrepreneurs and…
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Non-Profit R&D-Boosting Program Sets Record

A government-funded non-profit group tasked with linking Canadian academia and domestic technology startups has hit a major milestone. In the last year, the Mitacs internship program has connected 1,500 University of British Columbia (UBC) post-doctoral students with private-sector partners, officials said. The number is about double the internships Mitacs usually provides at the Vancouver-based university annually, as yearly totals usually fall between 500 and…
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The authors show that, despite the surprisingly complex origin of apicomplexans from algae, the alga-parasite transition actually occurred at least three times independently. Using single-cell genomics and transcriptomics from diverse uncultivated parasites, they found that two genera previously classified within the Apicomplexa, Piridium and Platyproteum, form separately branching lineages in phylogenomic analyses. Both retain cryptic plastids with genomic and metabolic features convergent with apicomplexans.
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UBC’s Carolina Tropini, an Assistant Professor in the School of Biomedical Engineering and the Department of Microbiology and Immunology, has been named as one of fourteen inspiring early-career researchers named across five CIFAR research programs. The CIFAR Azrieli Global Scholars program supports exceptional early-career researchers who show promise to be the research leaders of tomorrow. Through funding and mentorship, the…
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T-cells, white blood cells that can trigger or suppress immune responses, have long been seen as a cell type that could provide life-changing immunotherapies. Contrary to using chemotherapy or immunosuppressive drugs that have many negative side-effects, T-cell therapies work by amplifying natural human mechanisms. Dr. James Piret, a Professor at the Michael Smith Laboratories and the Department of Chemical & Biological…
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The University of British Columbia (UBC) has a long history of transforming research into impactful treatments, products, and services that contribute to the social and economic fabric of Canada. Through UBC’s applied research, accelerator, and incubator programs, the next generation of entrepreneurial talent receives critical support needed to take its ideas to the next level. That’s why the Honourable Navdeep…
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Scientists Enhance Important Tool Used to Research the Deadliest Form of Brain Cancer

The prognosis for patients diagnosed with GBM is extremely poor. Even with surgical removal of tumours followed by radiation and chemotherapy, 90 per cent of patients succumb to the disease within five years. Clearly, new therapies to tackle this deadly form of brain cancer are urgently needed. Using mice to study Glioblastoma multiforme (GBM), the most aggressive form of brain…
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Alzheimer’s disease (AD) disproportionately affects females. We determined whether physiological biomarkers (neuroplasticity, immune, stress, epigenetic) explain why females are more susceptible to AD than males using the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database. Methods Using the complete ADNI cohort, we analysed the effect of sex and APOE genotype (number of ε4 alleles) and sex and diagnosis (cognitively normal (CN), mild cognitive…
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The bacterial injectisome is a syringe-shaped macromolecular nanomachine utilized by many pathogenic Gram-negative bacteria. The essential role in bacterial infection make it an attractive target for the development of novel antibiotics and vaccines. Using cryo-EM, the authors have captured the injectisome core in multiple distinct assembly stages. This novel structural information allows us to understand how this complex assembles and functions, and paves the way for structure-based design of novel therapeutics.
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