BC Children’s Hospital Research Institute is pleased to congratulate the recipients of the 2019 Outstanding Achievement Awards and the 2019 BCCHR Studentships and Fellowships. Outstanding Achievement Awards The Outstanding Achievement Awards recognize trainee achievements in research aimed at improving the health and well-being of children and families. This year’s recipients are: Outstanding Achievement Award by an Undergraduate Student Jeff Holmes, Karakochuk…
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Poul Sorensen, a UBC professor in the department of pathology and laboratory medicine, has been awarded the 2019 Bloom Burton Award, recently presented at a gala in Toronto. Sorensen, a molecular pathologist and cancer biologist specializing in the genetics and biology of pediatric cancers, also received a $25,000 prize for being named a finalist for the award. The annual award honours…
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Medical professionals don’t always get to hear from the people whose lives they have changed, but one Alberta mother finally had the chance to thank the Vancouver-based doctor whose research helped save the life of her young son. Kayley Leeds’s son, Ashton, was five when he was diagnosed with Stage 4 thyroid cancer in 2014. This past week, Leeds spoke with…
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Single-cell RNA sequencing has enabled the decomposition of complex tissues into functionally distinct cell types. Often, investigators wish to assign cells to cell types through unsupervised clustering followed by manual annotation or via ‘mapping’ to existing data. However, manual interpretation scales poorly to large datasets, mapping approaches require purified or pre-annotated data and both are prone to batch effects. To…
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AbCellera, a biotech focusing on the discovery of therapeutic antibodies, is one of Vancouver’s top 10 fastest growing companies, according to the Globe and Mail’s list of Canada’s Top Growing Companies. The Report on Business ranks Canadian companies based on three-year revenue growth. “AbCellera is on a trajectory to become a Canadian anchor company. Greater Vancouver is home to world-class research…
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Using breakthrough proprietary and patented technology developed by BioHarvest Ltd, CannaVcell (the worldwide exclusive licensee of this technology for Cannabis applications) is announcing today the first ever production of Cannabis cells in suspension, with a cannabinoid profile identical to that of the source plant – without the need to grow the plant itself. This represents the successful completion of the…
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The authors found that a well-characterized DNA repair complex, called the MRN complex, had a new role in responding to DNA replication forks that have been blocked by collisions with the transcription machinery. While the MRN complex contains a nuclease activity, their data suggested that a non-nucleolytic scaffolding role of the complex is important to promote the recruitment of downstream repair factors to conflicts during replication.
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Congratulations to Dr. Liisa Galea, distinguished university scholar and professor in the department of psychology, for receiving the Convening & Collaborating (C2) award from the Michael Smith Foundation for Health Research. Dr. Liisa Galea and Shirley Weir, research user co-lead and founder of Menopause Chicks—along with a host of interdisciplinary collaborators—will be using this award to host a Women’s Health Conference, Brain Exchange: Engaging Inter-disciplinary Perspectives to Support Women’s…
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Recent Advances in Lipid Nanoparticle-Mediated mRNA Therapy

All cells function by an intricate mechanism that converts information stored as nucleic acid sequences (DNA) into messages (messenger RNA) for translation into functional products (protein). Endogenous checks and balances exist within this information flow, which can be leveraged as therapies to treat diseases closer to their genetic origin. The significant health opportunities of gene therapies are evident in the…
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